β-1,3-Glucan

Names

[ Name ]:
β-1,3-Glucan

[Synonym ]:
Paramylon
beta Glucan
Laminarin from Laminaria digitata
|A-1,3-Glucan from Euglena gracilis
|A-D-Glucan from barley

Biological Activity

[Description]:

β-1,3-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₃₀O₁₅

[ Molecular Weight ]:
486.42200

[ Exact Mass ]:
486.15800

[ PSA ]:
237.45000

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ3985000

CHEMICAL NAME :: beta-D-Glucan, (1-3)-

CAS REGISTRY NUMBER :: 9051-97-2

LAST UPDATED :: 199512

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 19 mg/kg/6W-I

TOXIC EFFECTS :: Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: ARDEAC Archives of Dermatology. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.82- 1960- Volume(issue)/page/year: 123,751,1987

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
LZ3985000

Articles

How carbohydrates sculpt cells: chemical control of morphogenesis in the yeast cell wall.

Nat. Rev. Microbiol. 11(9) , 648-55, (2013)

In budding yeast, the neck that connects the mother and daughter cell is the site of essential functions such as organelle trafficking, septum formation and cytokinesis. Therefore, the morphology of t...

An initial event in the insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein.

Biochemistry 52(1) , 161-70, (2013)

In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease c...

Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice.

Arthritis Rheumatology 66(7) , 1755-67, (2014)

Spondyloarthritides (SpA) occur in 1% of the population and include ankylosing spondylitis (AS) and arthropathy of inflammatory bowel disease (IBD), with characteristic spondylitis, arthritis, enthesi...