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Z-Ala-Arg-Arg-AMC hydrochloride salt

Names

[ CAS No. ]:
90468-18-1

[ Name ]:
Z-Ala-Arg-Arg-AMC hydrochloride salt

[Synonym ]:
z-ala-arg-arg-7-amino-4-methylcoumarin
z-ala-arg-arg-amc hydrochloride salt
z-l-alanyl-l-arginyl-l-arginine-7-amido-4-methylcoumarin hydrochloride
z-arr-amc,2hcl
z-ala-arg-arg-amc
z-ala-arg-arg-amc hcl

Biological Activity

[Description]:

Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

[References]

[1]. Crawford LJ, et al. Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132. Cancer Res. 2006 Jun 15;66(12):6379-86.  

Chemical & Physical Properties

[ Molecular Formula ]:
C33H44N10O7

[ Molecular Weight ]:
692.76500

[ Exact Mass ]:
692.33900

[ PSA ]:
279.64000

[ LogP ]:
4.47850

Related Compounds