ec 1.1.1.28

Names

[ Name ]:
ec 1.1.1.28

[Synonym ]:
D-(-)-Lactate dehydrogenase
D-(-)-Lactate dehydrogenase (NAD)
D-Lactate dehydrogenase

Biological Activity

[Description]:

D-Lactate dehydrogenase (D-LDH) is an oxidoreductase that uses NAD+ or NADP+ as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase

[References]

[1]. O Dym, et al. The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9413-8.

Chemical & Physical Properties

[ Appearance of Characters ]:
suspension | yellow

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Characterization of D-lactate dehydrogenase producing D-3-phenyllactic acid from Pediococcus pentosaceus.

Biosci. Biotechnol. Biochem. 76(4) , 853-5, (2012)

D-Lactate dehydrogenase (D-LDH) from Pediococcus pentosaceus ATCC 25745 was found to produce D-3-phenyllactic acid from phenylpyruvate. The optimum pH and temperature for enzyme activity were pH 5.5 a...

Characterization of D-lactate dehydrogenase from Pediococcus acidilactici that converts phenylpyruvic acid into phenyllactic acid.

Biotechnol. Lett. 34(5) , 907-11, (2012)

The gene coding for D-lactate dehydrogenase (D-LDH) from Pediococcus acidilactici DSM 20284 was cloned and expressed in E. coli. The recombinant enzyme was purified by nickel-affinity chromatography. ...

Secretome profile of mouse oocytes after activation using mass spectrum.

J. Assist. Reprod. Genet. 29(8) , 765-71, (2012)

Mammalian oocytes undergo a cortical reaction after fertilization, releasing cortical granules and other proteins into the perivitelline space and inhibiting polyspermy. Few studies have evaluated the...