Mung Bean Nuclease

Names

[ Name ]:
Mung Bean Nuclease

[Synonym ]:
EINECS 206-864-7
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-
1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic Acid
T66 BV EN GNJ CVQ E2 H1
NegGram
WIN-18320
WINTOMYLON
nalidixic acid
MFCD00131010

Biological Activity

[Description]:

Serratia marcescens nuclease is a nonspecific nuclease. Serratia marcescens nuclease has broad utility due to its potent digestive activity toward both DNA and RNA[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. "Vafina G, et al. Endonuclease from Gram-Negative Bacteria Serratia marcescens Is as Effective as Pulmozyme in the Hydrolysis of DNA in Sputum. Front Pharmacol. 2018;9:114. Published 2018 Feb 16. doi:"

[2]. "Friedhoff P, et al. A procedure for renaturation and purification of the extracellular Serratia marcescens nuclease from genetically engineered Escherichia coli. Protein Expr Purif. 1994;5(1):37-43. "

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
413.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₂N₂O₃

[ Molecular Weight ]:
232.235

[ Flash Point ]:
203.6±28.7 °C

[ Exact Mass ]:
232.084793

[ LogP ]:
1.19

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.605

[ Storage condition ]:
20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

Phospho-iTRAQ: assessing isobaric labels for the large-scale study of phosphopeptide stoichiometry.

J. Proteome Res. 14(2) , 839-49, (2015)

The ability to distinguish between phosphopeptides of high and low stoichiometry is essential to discover the true extent of protein phosphorylation. We here extend the strategy whereby a peptide samp...

Oligosaccharide and substrate binding in the starch debranching enzyme barley limit dextrinase.

J. Mol. Biol. 427(6 Pt B) , 1263-77, (2015)

Complete hydrolytic degradation of starch requires hydrolysis of both the α-1,4- and α-1,6-glucosidic bonds in amylopectin. Limit dextrinase (LD) is the only endogenous barley enzyme capable of hydrol...

Synthetic antibodies and peptides recognizing progressive multifocal leukoencephalopathy-specific point mutations in polyomavirus JC capsid viral protein 1.

MAbs 7 , 681-92, (2015)

Polyomavirus JC (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a rare and frequently fatal brain disease that afflicts a small fraction of the immune-compromised pop...