Deoxyribonuclease II

Names

[ Name ]:
Deoxyribonuclease II

Biological Activity

[Description]:

Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Evans CJ, et al. DNase II: genes, enzymes and function. Gene. 2003 Dec 11;322:1-15.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Identification of neutral and acidic deoxyribonuclease activities in Tetrahymena thermophila life stages.

Eur. J. Protistol. 51 , 173-85, (2015)

Deoxyribonucleases (DNases) play a major role in apoptotic DNA fragmentation/degradation, and apoptotic-like DNA degradation is also observed during conjugation of the ciliate Tetrahymena thermophila;...

The story of DNase II: a stifled death-wish leads to self-harm.

Eur. J. Immunol. 40(9) , 2376-8, (2010)

DNase II is an endonuclease which plays a fundamental role in the degradation of DNA from both apoptotic cells, and nuclei extruded from red blood cells during erythropoiesis: important tasks, conside...

DNase 2 is the main DNA-degrading enzyme of the stratum corneum.

PLoS ONE 6(3) , e17581, (2011)

The cornified layer, the stratum corneum, of the epidermis is an efficient barrier to the passage of genetic material, i.e. nucleic acids. It contains enzymes that degrade RNA and DNA which originate ...