Hemocyanin

Names

[ Name ]:
Hemocyanin

[Synonym ]:
MFCD00131280

Biological Activity

[Description]:

Hemocyanin is a large copper-containing respiratory protein. Hemocyanin is an important non-specific innate immune defense molecule with phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

[Target]

Human Endogenous Metabolite

[References]

[1]. Xianliang Zhao, et al. Protein Diversity and Immune Specificity of Hemocyanin From Shrimp Litopenaeus vannamei. Front Immunol. 2021 Dec 7;12:772091.

Chemical & Physical Properties

[ Storage condition ]:
-20C

Safety Information

[ Hazard Statements ]:
H412

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ RIDADR ]:
NONH for all modes of transport

Articles

Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing.

Mol. Cell. Biol. 34(23) , 4343-54, (2014)

The Wiskott-Aldrich syndrome protein (WASp) is important for actin polymerization in T cells and for their migration. WASp-interacting protein (WIP) binds to and stabilizes WASp and also interacts wit...

Identification and characterization of the related immune-enhancing proteins in crab Scylla paramamosain stimulated with rhubarb polysaccharides.

Mol. Immunol. 57(2) , 263-73, (2014)

Recently, considerable interest has been focused on immunostimulants to reduce diseases in crab aquaculture. However, information regarding to the related immune-enhancing proteins in crabs is not ava...

Tofacitinib suppresses antibody responses to protein therapeutics in murine hosts.

J. Immunol. 193(1) , 48-55, (2014)

Immunogenicity remains the "Achilles' heel" of protein-based therapeutics. Anti-drug Abs produced in response to protein therapeutics can severely limit both the safety and efficacy of this expanding ...