2-Aminodiphenyl
Names
[ CAS No. ]:
90-41-5
[ Name ]:
2-Aminodiphenyl
[Synonym ]:
2-phenylaniline
MFCD00007126
(1,1'-BIPHENYL)AMINE
PHENYLANILINE
EINECS 201-990-9
2-Biphenylamine
biphenylamine
[1,1'-Biphenyl]-2-amine
2-Aminobiphenyl
biphenyl-2-amine
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
299.0±0.0 °C at 760 mmHg
[ Melting Point ]:
47-50 °C(lit.)
[ Molecular Formula ]:
C12H11N
[ Molecular Weight ]:
169.222
[ Flash Point ]:
149.9±14.6 °C
[ Exact Mass ]:
169.089142
[ PSA ]:
26.02000
[ LogP ]:
2.68
[ Vapour density ]:
5.9 (vs air)
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.619
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
<0.01 g/100 mL at 21 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DU8850000
- CHEMICAL NAME :
- 2-Biphenylamine
- CAS REGISTRY NUMBER :
- 90-41-5
- BEILSTEIN REFERENCE NO. :
- 0471874
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C12-H11-N
- MOLECULAR WEIGHT :
- 169.24
- WISWESSER LINE NOTATION :
- ZR BR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2340 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1020 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 137 gm/kg/13W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in spleen Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 gm/kg/14D-C
- TOXIC EFFECTS :
- Blood - changes in spleen
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 328 gm/kg/13W-C
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in bone marrow (not otherwise specified) Blood - changes in leukocyte (WBC) count
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 1100 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 265,45,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82091 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 700 (estimated)
Safety Information
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R40;R52/53
[ Safety Phrases ]:
S36/37-S61
[ RIDADR ]:
3077.0
[ WGK Germany ]:
3
[ RTECS ]:
DV5530000
[ Hazard Class ]:
9.0
[ HS Code ]:
29214980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%