3-epi-Isocucurbitacin B

Names

[ Name ]:
3-epi-Isocucurbitacin B

[Synonym ]:
(23E)-1,16,20-Trihydroxy-9,10,14-trimethyl-2,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
Estr-5-ene-2,11-dione, 17-[(3E)-5-(acetyloxy)-1-hydroxy-1,5-dimethyl-2-oxo-3-hexen-1-yl]-3,16-dihydroxy-4,4,9,14-tetramethyl-

Biological Activity

[Description]:

3-epi-Isocucurbitacin B (Compound 5) is a cucurbitane triterpene derived from Trichosanthes kirilowii. 3-epi-Isocucurbitacin B shows significant cytotoxicity to human tumor cells A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT15[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Shi Yong Ryu, et al. Antitumor activity of Trichosanthes kirilowii. 1994;17(5):348–353.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
702.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₂H₄₆O₈

[ Molecular Weight ]:
558.70

[ Flash Point ]:
219.9±26.4 °C

[ Exact Mass ]:
558.319275

[ PSA ]:
138.20000

[ LogP ]:
2.06

[ Vapour Pressure ]:
0.0±5.0 mmHg at 25°C

[ Index of Refraction ]:
1.568

3-epi-Isocucurbitacin B

Names

Biological Activity

Chemical & Physical Properties

Related Compounds