FmocNH-PEG4-t-butyl acetate
Names
[ CAS No. ]:
894427-95-3
[ Name ]:
FmocNH-PEG4-t-butyl acetate
[Synonym ]:
tert-butyl 5-N-(9-fluorenylmethyloxycarbonyl)-15-aza-3,6,9,12-tetraoxa-pentadecanoate
Biological Activity
[Description]:
FmocNH-PEG4-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C29H39NO8
[ Molecular Weight ]:
529.62200
[ Exact Mass ]:
529.26800
[ PSA ]:
101.55000
[ LogP ]:
4.32410