2-Chlorobenzaldehyde
Names
[ CAS No. ]:
89-98-5
[ Name ]:
2-Chlorobenzaldehyde
[Synonym ]:
USAF m-7
2-CHLOROBENZALDEHYDE FOR PHARMA SYNTHESIS
O-CHLOROBENZALDEHYDE( OCBA)
o-Chloroformylbenzene
2-CHLOROBENZALDEHYDE (1 LT )
o-chloro-benzaldehyde
O CHLOROBENZALDEHYDE
2-Clorobenzaldeide
2-chloro-benzaldehyde
OCAD
2-Chlorbenzaldehyd
o-chloro-benzaldehyd
Benzaldehyde, 2-chloro-
ortho-chloro benzaldehyde
OCBA
o-Chlor-benzaldehyd
ORTHOCHLOROBENZALDEHYDE
EINECS 201-956-3
UNII-QHR24X1LXK
VHR BG
MFCD00003304
o -Chlorobenzaldehyde
o-Chlorobenzaldehyde
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
211.9±0.0 °C at 760 mmHg
[ Melting Point ]:
9-11 °C(lit.)
[ Molecular Formula ]:
C7H5ClO
[ Molecular Weight ]:
140.567
[ Flash Point ]:
87.8±0.0 °C
[ Exact Mass ]:
140.002899
[ PSA ]:
17.07000
[ LogP ]:
2.33
[ Vapour density ]:
4.84 (vs air)
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.585
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, iron, strong reducing agents. Moisture and light-sensitive.
[ Water Solubility ]:
0.1-0.5 g/100 mL at 24 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU5075000
- CHEMICAL NAME :
- Benzaldehyde, o-chloro-
- CAS REGISTRY NUMBER :
- 89-98-5
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C7-H5-Cl-O
- MOLECULAR WEIGHT :
- 140.57
- WISWESSER LINE NOTATION :
- VHR BG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2160 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533437
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533437
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 8500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 31,563,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2696 No. of Facilities: 100 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 739 (estimated) No. of Female Employees: 284 (estimated)
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S45
[ RIDADR ]:
UN 3265 8/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
CU5075000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2913000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299035
[ Summary ]:
2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%
Articles
J. Org. Chem. 77(20) , 9094-101, (2012)
The nonaccessibility of phenyl cations by irradiation of electron-poor aryl chlorides was circumvented by transforming the carbonyl group of aromatic ketones or aldehydes into the corresponding 1,3-di...
Experimental and theoretical studies of the products of addition-elimination reactions between benzil dihydrazone and three isomeric chlorobenzaldehydes.Acta Crystallogr. C Struct. Chem. 71 , 554-63, (2015)
A series of mono- and di-Schiff bases formed between benzil dihydrazone {BDH; systematic name: (1Z)-[(2E)-2-hydrazinylidene-1,2-diphenylethylidene]hydrazine} and three isomeric chlorobenzaldehydes wer...
β-Olefination of 2-alkynoates leading to trisubstituted 1,3-dienes.Org. Lett. 13(13) , 3418-21, (2011)
A phosphine-mediated olefination of 2-alkynoates with aldehydes forming 1,3-dienes with high E-selectivity and up to 88% yield is described. Reaction conditions are optimized and reactions are demonst...