2-sec-Butylphenol
Names
[ CAS No. ]:
89-72-5
[ Name ]:
2-sec-Butylphenol
[Synonym ]:
2-sec.Butylfenol
6-sec-butyl-phenol
O-S-BUTYLPHENOL
o-sec-butyl-pheno
2-sec.-butylphenol
2-sek.Butylphenol
Phenol,o-sec-butyl
EINECS 201-933-8
O-SEC-BUTYLPHENOL
2-sec-Butylphenol
ortho-sec-butylphenol
OSBP
MFCD00002225
methylpropylphenol
Chemical & Physical Properties
[ Density]:
0.982 g/mL at 25 °C(lit.)
[ Boiling Point ]:
226-228 °C(lit.)
[ Melting Point ]:
12 °C(lit.)
[ Molecular Formula ]:
C10H14O
[ Molecular Weight ]:
150.21800
[ Flash Point ]:
234 °F
[ Exact Mass ]:
150.10400
[ PSA ]:
20.23000
[ LogP ]:
2.90570
[ Vapour Pressure ]:
0.03 mm Hg ( 20 °C)
[ Index of Refraction ]:
n20/D 1.522(lit.)
[ Stability ]:
Stable, but air sensitive. Incompatible with acid chlorides, acid anhydrides, bases, strong oxidizing agents, copper and its alloys, brass.
[ Water Solubility ]:
Insoluble.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SJ8920000
- CHEMICAL NAME :
- Phenol, o-sec-butyl-
- CAS REGISTRY NUMBER :
- 89-72-5
- BEILSTEIN REFERENCE NO. :
- 1210026
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 21
- MOLECULAR FORMULA :
- C10-H14-O
- MOLECULAR WEIGHT :
- 150.24
- WISWESSER LINE NOTATION :
- QR BY2&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,224,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,224,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1350,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 5,84,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 600 mg/kg
- REFERENCE :
- 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 5,84,1986 *** REVIEWS *** ACGIH TLV-TWA 31 mg/m3 (5 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (30 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 5 ppm (31 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 5 ppm (30 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (30 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (30 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (30 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (30 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-sec-BUTYLPHENOL-air:10H TWA 5 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83612 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 316 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R22;R34
[ Safety Phrases ]:
S26-S27-S28-S36/37/39-S45
[ RIDADR ]:
UN 3145 8/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
SJ8920000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2907191090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2907191090
[ Summary ]:
2907191090 2-(sec-butyl)phenol。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:4.0%。General tariff:11.0%
Articles
Biodegradation 21(2) , 157-65, (2010)
A novel bacterium capable of utilizing 2-sec-butylphenol as the sole carbon and energy source, Pseudomonas sp. strain MS-1, was isolated from freshwater sediment. Within 30 h, strain MS-1 completely d...
Induction of CYP102 (cytochrome P450BM-3) in Bacillus megaterium by 17 beta-estradiol and 4-sec-butylphenol.Biochem. Biophys. Res. Commun. 244(3) , 868-72, (1998)
CYP102 (Cytochrome P450BM-3) is induced in Bacillus megaterium by barbiturates, peroxisome proliferators, and nonsteroidal anti-inflammatory drugs. We now describe the induction of CYP102 in B. megate...
Spectrophotometric determination of nitrate in vegetable products using 2-sec-butylphenol.Analyst 107(1271) , 190-4, (1982)