15-Acetyl-deoxynivalenol
Names
[ CAS No. ]:
88337-96-6
[ Name ]:
15-Acetyl-deoxynivalenol
[Synonym ]:
15-ADON
15-ACETYLDEOXYNIVALENOL
Deoxynivalenol 15-Acetate
15-acetoxy-3,7-dihydroxy-12,13-epoxytrichothec-9-en-8-one
15-O-acetyl-4-deoxynivalenol
15-ACETYLVOMITOXIN
15-acetyl
15-Acetyl-4-deoxynivalenol
3-ACETYL-D3-DEOXYNIVALENOL
15-ACDON
DON-15-acetate
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.42g/cm3
[ Boiling Point ]:
518.8ºC at 760 mmHg
[ Melting Point ]:
185°C-187°C
[ Molecular Formula ]:
C17H22O7
[ Molecular Weight ]:
338.35200
[ Flash Point ]:
2ºC
[ Exact Mass ]:
338.13700
[ PSA ]:
105.59000
[ Index of Refraction ]:
1.595
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YD0155000
- CHEMICAL NAME :
- Trichothec-9-en-8-one, 15-(acetyloxy)-12,13-epoxy-3,7-dihydroxy-, (3-alpha,7-alpha)-
- CAS REGISTRY NUMBER :
- 88337-96-6
- LAST UPDATED :
- 198708
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H22-O7
- MOLECULAR WEIGHT :
- 338.39
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 34 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - ulceration or bleeding from small intestine Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder Blood - changes in spleen
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 25,155,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 113 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 50,1304,1985
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300-H311-H331
[ Precautionary Statements ]:
P261-P264-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T,Xn,F
[ Risk Phrases ]:
23/24/25-36-20/21/22-11
[ Safety Phrases ]:
36/37-45-26
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
YD0155000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
29329990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. A. 1419 , 37-44, (2015)
An LC-MS/MS (QqQ) method has been developed and validated for simultaneous determination of the following trichothecenes in UHT cow milk: nivalenol (NIV), deoxynivalenol (DON), deepoxy-deoxynivalenol ...
Innate Immune Sensing of Fusarium culmorum by Mouse Dendritic Cells.J. Toxicol. Environ. Health A 78 , 871-85, (2015)
Chronic inhalation of grain dust is associated with asthma and chronic bronchitis in grain worker populations. Exposure to fungal particles was postulated to be an important etiologic agent of these p...
Determination of the Mycotoxin Content in Distiller's Dried Grain with Solubles Using a Multianalyte UHPLC-MS/MS Method.J. Agric. Food Chem. 63 , 9441-51, (2015)
There are more than 300 potential mycotoxins that can contaminate food and feed and cause adverse effects in humans and animals. The data on the co-occurrence of mycotoxins in novel animal feed materi...