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Amlodipine intermediate

Names

[ CAS No. ]:
88150-62-3

[ Name ]:
Amlodipine intermediate

[Synonym ]:
3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-{[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]methyl}-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate
EINECS 413-410-3
Amlodipine intermediate
3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
T56 BVNVJ C2O1- BT6M DHJ CVO2 DR BG& EVO1 F1
3-O-ethyl 5-O-methyl 4-(2-chlorophenyl)-2-[2-(1,3-dioxoisoindol-2-yl)ethoxymethyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
MFCD07782096
Amlodipine Impurity 1

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
654.1±55.0 °C at 760 mmHg

[ Melting Point ]:
140-145ºC

[ Molecular Formula ]:
C28H27ClN2O7

[ Molecular Weight ]:
538.976

[ Flash Point ]:
349.4±31.5 °C

[ Exact Mass ]:
538.150696

[ PSA ]:
111.24000

[ LogP ]:
6.38

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.589

[ Storage condition ]:
Refrigerator

Safety Information

[ Risk Phrases ]:
R53

[ Safety Phrases ]:
61

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream


Related Compounds