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Bismuth Subcitrate Potassium

Names

[ CAS No. ]:
880149-29-1

[ Name ]:
Bismuth Subcitrate Potassium

[Synonym ]:
Bismuth subcitrate potassium
S4093

Biological Activity

[Description]:

Bismuth subcitrate potassium is an antibiotic against 12 C. pyloridis strains with MIC50 of 8 ug/ml[1]. Bismuth subcitrate potassium is used to treat diseases of the upper gastrointestinal tract infected with Helicobacter pylori[2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC50: 8 ug/ml (C. pyloridis)[1]


[References]

[1]. Van Caekenberghe DL, et al. In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori). Antimicrob Agents Chemother. 1987 Sep;31(9):1429-30.

[2]. Malfertheiner P, et al. Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. Lancet. 2011 Mar 12;377(9769):905-13.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H8BiK5O14

[ Molecular Weight ]:
782.67100

[ Exact Mass ]:
781.80600

[ PSA ]:
281.24000

[ Storage condition ]:
-20℃

Related Compounds