Eupalinolide A

Names

[ Name ]:
Eupalinolide A

[Synonym ]:
Eupalinolide A
2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4R,6Z,9S,10E,11aR)-9-(acetyloxy)-6-[(acetyloxy)methyl]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)-
(3aR,4R,6Z,9S,10E,11aR)-9-Acetoxy-6-(acetoxymethyl)-10-methyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methyl-2-butenoate

Biological Activity

[Description]:

Eupalinolide B is a germacrane sesquiterpene isolated from Eupatorium lindleyanum. Eupalinolide B demonstrates potent cytotoxicity against A-549, BGC-823 and HL-60 tumour cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Yang NY, et al. Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. J Asian Nat Prod Res. 2007 Apr-Aug;9(3-5):339-45.

Chemical & Physical Properties

[ Density]:
1.24±0.1 g/cm3 (20 ºC 760 Torr)

[ Boiling Point ]:
618.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₃₀O₉

[ Molecular Weight ]:
462.490

[ Flash Point ]:
205.4±25.0 °C

[ Exact Mass ]:
462.188995

[ PSA ]:
125.43000

[ LogP ]:
2.50

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.541

Related Compounds

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