IWP-2-V2

Names

[ Name ]:
IWP-2-V2

[Synonym ]:
2-[(3-Benzyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[[3,4,6,7-tetrahydro-4-oxo-3-(phenylmethyl)thieno[3,2-d]pyrimidin-2-yl]thio]-

Biological Activity

[Description]:

IWP-2-V2 is a IWP-2 (HY-13912) analogue that retains activity against the Wnt/β-catenin pathway[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Stem Cell/Wnt >> Wnt

[References]

[1]. Chen B, et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol. 2009 Feb;5(2):100-7. doi: 10.1038/nchembio.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₂₃H₂₀N₄O₂S₃

[ Molecular Weight ]:
480.63

[ Exact Mass ]:
480.074829

[ PSA ]:
155.72000

[ LogP ]:
5.33

[ Index of Refraction ]:
1.770

IWP-2-V2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds