Iristectorigenin B

Names

[ Name ]:
Iristectorigenin B

[Synonym ]:
4H-1-Benzopyran-4-one,5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-6-methoxy
3',5,7-Trihydroxy-4',6-dimethoxyisoflavone
Iristectorigenin
5,7-Dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
5,7-dihydroxy-3-(3-hydroxy-4-methoxy-phenyl)-6-methoxy-chromen-4-one
Iristectorigenin A
Iristectorigenin B

Biological Activity

[Description]:

Iristectorigenin B (Iristectrigenin B) is a liver X receptor (LXR) modulator. Iristectrigenin B stimulates the transcriptional activity of both LXR-α and LXR-β[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> LXR

[References]

[1]. Hee-jin Jun, et al. Iristectorigenin B isolated from Belamcanda chinensis is a liver X receptor modulator that increases ABCA1 and ABCG1 expression in macrophage RAW 264.7 cells. Biotechnol Lett. 2012 Dec;34(12):2213-21.

Chemical & Physical Properties

[ Density]:
1.483g/cm3

[ Boiling Point ]:
621.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₁₄O₇

[ Molecular Weight ]:
330.28900

[ Flash Point ]:
232.8ºC

[ Exact Mass ]:
330.07400

[ PSA ]:
109.36000

[ LogP ]:
2.59400

[ Index of Refraction ]:
1.67

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%