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Tyr-Somatostatin-28

Names

[ CAS No. ]:
86649-84-5

[ Name ]:
Tyr-Somatostatin-28

[Synonym ]:
Tyr-Somatostatin-28
Tyr-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys
YSANSNPAMAPRERKAGCKNFFWKTFTSC

Biological Activity

[Description]:

Tyr-Somatostatin-28 is a somatostatin that adds a Tyrosine amino acid to Somatostatin-28[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[In Vitro]

在豚鼠原代培养的胰腺腺泡细胞的基底外侧质膜中，Insulin (Insulin (human) (HY-P0035)) 增加 Ca2+ 激活的 K+ 通道的 p 值，Tyr-Somatostatin-28 (0.3 μM) 可逆转这种情况[1]。

[References]

[1]. M Yanagisawa, et al. A reciprocal regulation of Ca(2+)-activated K(+) channel by insulin and somatostatin in guinea-pig pancreatic acinar cells. Jpn J Physiol. 2001 Jun;51(3):355-63.  

Chemical & Physical Properties

[ Molecular Formula ]:
C146H216N42O41S3

[ Molecular Weight ]:
3311.73000

[ Exact Mass ]:
3309.53000

[ PSA ]:
1442.04000

[ LogP ]:
1.02770

Related Compounds