5,7,3',4'-Tetramethoxyflavone

Names

[ CAS No. ]:
855-97-0

[ Name ]:
5,7,3',4'-Tetramethoxyflavone

[Synonym ]:
Luteolin tetramethyl ether
Tetramethoxyluteolin
5,7,3',4'-Tetramethylluteolin
3',4',5,7-Tetramethyl-luteolin
5,7,3',4'-tetramethoxyflavone
MFCD00017558
Tetramethylluteolin
3',4',5,7-Tetramethoxyflavone
5,7,3'-trimethoxy 4'-hydroxyflavone

Biological Activity

[Description]:

5,7,3',4'-Tetramethoxyflavone, one of the major polymethoxyflavones (PMFs) isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Wu L, et al. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling in vivo and in vitro. Biochem Biophys Res Commun. 2014 Sep 26;452(3):682-8.

Chemical & Physical Properties

[ Density]:
1.243g/cm3

[ Boiling Point ]:
528.8ºC at 760 mmHg

[ Melting Point ]:
195-197°C

[ Molecular Formula ]:
C₁₉H₁₈O₆

[ Molecular Weight ]:
342.34300

[ Flash Point ]:
233.9ºC

[ Exact Mass ]:
342.11000

[ PSA ]:
67.13000

[ LogP ]:
3.49440

[ Index of Refraction ]:
1.574

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%