3,4-Difluorobenzyl bromide
Names
[ CAS No. ]:
85118-01-0
[ Name ]:
3,4-Difluorobenzyl bromide
[Synonym ]:
3, 4-DIFLUOROBENZYL BROMIDE
3,4-Difluorobenzylbromide
alpha-Bromo-3,4-difluorotoluene
3,4-Difluoro Bromine Benzyl
3 4-DIFLUOROBENZYL BROMIDE
4-(BROMOMETHYL)-1,2-DIFLUORO-BENZENE
3,4-DIFLUORBENZYLBROMID
Benzene, 4-(bromomethyl)-1,2-difluoro-
MFCD00009889
4-(Bromomethyl)-1,2-difluorobenzene
FR BF D1E
α-Bromo-3,4-difluorotoluene
ALPHA-BROMO-3,4-DIFLUOROTOLUEN
3,4-DIFLUORO-BROMOBENZYL
EINECS 285-653-1
3,4-Difluorobenzyl bromide
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
195.5±25.0 °C at 760 mmHg
[ Molecular Formula ]:
C7H5BrF2
[ Molecular Weight ]:
207.015
[ Flash Point ]:
79.4±0.0 °C
[ Exact Mass ]:
205.954269
[ LogP ]:
2.93
[ Vapour Pressure ]:
0.6±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.523
MSDS
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S23-S26-S27-S36/37/39-S45
[ RIDADR ]:
UN 3265 8/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2903999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903999090
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 22(8) , 2922-6, (2012)
A series of benzothiophene-based phosphonates was synthesized and many analogs within the series were shown to be potent antagonists of the TRPM8 channel. The compounds were obtained as a racemic mixt...