Arcapillin

Names

[ Name ]:
Arcapillin

[Synonym ]:
Arcapillin
5,2',4'-trihydroxy-6,7,5'-trimethoxyflavone
2',4',5-trihydroxy-5',6,7-trimethoxyflavone
2-(2,4-dihydroxy-5-methoxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one

Biological Activity

[Description]:

Arcapillin is a flavonoid that can be isolated from Artemisia capillaris Thunb. Arcapillin has antispasmodic activity. Arcapillin also has moderate PTP1B inhibitory activity[1][2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Neurological Disease

[Target]

PTP1B[1]

[References]

[1]. Lubna F. Abu-Niaaj, et al. Evaluation of Antispasmodic Effect of Arcapillin on Smooth Muscles of Rats. PHARMACOGN J, VOL 11, ISSUE 4, JUL-AUG, 2019.

[2]. Nurul Islam M, Jet al. Potent α-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris. Arch Pharm Res. 2013 May;36(5):542-52.

Chemical & Physical Properties

[ Density]:
1.461g/cm3

[ Boiling Point ]:
634.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₆O₈

[ Molecular Weight ]:
360.31500

[ Flash Point ]:
233.3ºC

[ Exact Mass ]:
360.08500

[ PSA ]:
118.59000

[ LogP ]:
2.60260

[ Index of Refraction ]:
1.649

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.