Fmoc-ser-ome

Names

[ Name ]:
Fmoc-ser-ome

[Synonym ]:
Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester
Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]serinate
methyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate
Fmoc-Ser-Ome

Biological Activity

[Description]:

Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Tamiaki H, et al. Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores. Bioorg Med Chem. 2014 Feb 15;22(4):1421-8.

[2]. Kärkkäinen TS, et al. Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides. Carbohydr Res. 2008 Jul 21;343(10-11):1830-4.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
579.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₉NO₅

[ Molecular Weight ]:
341.358

[ Flash Point ]:
304.2±28.7 °C

[ Exact Mass ]:
341.126312

[ PSA ]:
88.35000

[ LogP ]:
3.25

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Storage condition ]:
-15°C

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%