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ANAGRELIDE HCL MONOHYDRATE

Names

[ CAS No. ]:
823178-43-4

[ Name ]:
ANAGRELIDE HCL MONOHYDRATE

[Synonym ]:
Anagrelide hydrochloride monohydrate
6,7-Dichloro-1,5-dihydroimidazo(2,1-b)quinazolin-2(3H)-one monohydrochloride monohydrate
O374
UNII-YTM763Y5C8
YTM763Y5C8
Anagrelide hydrochloride hydrate (JAN)
Anagrelide HCl monohydrate

Biological Activity

[Description]:

Anagrelide hydrochloride monohydrate is a imidazoquinazoline agent. Anagrelide hydrochloride monohydrate decreases the level of platelets in blood, prevents blood clots formation. Anagrelide hydrochloride monohydrate can be used for research of essential thrombocythaemia (ET) and thrombocythaemia associated with polycythaemia vera (PV)[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Research Areas >> Others

[Target]

PDE3


[References]

[1]. Pescatore SL, et al. Anagrelide: a novel agent for the treatment of myeloproliferative disorders. Expert Opin Pharmacother. 2000 Mar;1(3):537-46.  

[2]. Mahajan R, et al. Phosphodiesterase inhibitors and their role in therapeutics[J]. Journal of Research in Medical Education & Ethics, 2013, 3(2): 115-123.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H10Cl3N3O2

[ Molecular Weight ]:
310.56400

[ Exact Mass ]:
308.98400

[ PSA ]:
57.42000

[ LogP ]:
2.31340

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds