5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-ADENOSINE

Names

[ Name ]:
5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-ADENOSINE

[Synonym ]:
5'-O-dimethoxytrityladenosine
5'-O-(p,p'-dimethoxytrityl)adenosine
Adenosine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]
5'-O-DMT-adenosine
5'-O-(4,4'-dimethoxytrityl)-adenosine
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine

Biological Activity

[Description]:

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₁N₅O₆

[ Molecular Weight ]:
569.61

[ Exact Mass ]:
569.22700

[ PSA ]:
147.00000

[ LogP ]:
3.63480

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%