N-Desethyloxybutynin hydrochloride

Names

[ Name ]:
N-Desethyloxybutynin hydrochloride

[Synonym ]:
DESETHYL OXYBUTYNIN HCL
a-Cyclohexyl-a-hydroxybenzeneaceticacid4-(Ethylamino)-2-butynylEster,HClSalt
A-CYCLOHEXYL-A-HYDROXYBENZENEACETIC ACID 4-(ETHYLAMINO)-2-BUTYNYL ESTER,HYDROCHLORIDE SALT
racDesethyl Oxybutynin Hydrochloride

Biological Activity

[Description]:

N-Desethyloxybutynin hydrochloride is an active metabolite of Oxybutynin. N-Desethyloxybutynin hydrochloride binds to mAChRs in isolated? human bladder and human parotid gland with pKi values of 8.2 and 8.7, respectively[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> mAChR

[References]

[1]. Claudine M Baldwin, et al. Transdermal oxybutynin. Drugs. 2009;69(3):327-37.

Chemical & Physical Properties

[ Melting Point ]:
136-138ºC

[ Molecular Formula ]:
C₂₀H₂₈ClNO₃

[ Molecular Weight ]:
365.89400

[ Exact Mass ]:
365.17600

[ PSA ]:
58.56000

[ LogP ]:
3.80350

Related Compounds

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