Kojic acid dipalmitate

Names

[ Name ]:
Kojic acid dipalmitate

[Synonym ]:
(5-hexadecanoyloxy-4-oxopyran-2-yl)methyl hexadecanoate
6-[(hexadecanoyloxy)methyl]-4-oxo-4H-pyran-3-yl hexadecanoate
4-Oxo-6-[(palmitoyloxy)methyl]-4H-pyran-3-yl palmitate
MFCD03840587
Hexadecanoic acid, 4-oxo-6-[[(1-oxohexadecyl)oxy]methyl]-4H-pyran-3-yl ester
EINECS 207-922-4

Biological Activity

[Description]:

Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[In Vitro]

Kojic acid dipalmitate 可有效抑制皮肤中酪氨酸酶活性，从而抑制黑色素形成。Kojic acid dipalmitate 比 Kojic Acid (HY-W050154) 更有效[1]。

[References]

[1]. Madhogaria S, et al. Leucoderma after use of a skin-lightening cream containing kojic dipalmitate, liquorice root extract and Mitracarpus scaber extract. Clin Exp Dermatol. 2010 Jun;35(4):e103-5.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
684.7±55.0 °C at 760 mmHg

[ Melting Point ]:
92-96ºC

[ Molecular Formula ]:
C₃₈H₆₆O₆

[ Molecular Weight ]:
618.927

[ Flash Point ]:
273.9±31.5 °C

[ Exact Mass ]:
618.485962

[ PSA ]:
82.81000

[ LogP ]:
15.30

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.492

MSDS

Click to get detail MSDS

Safety Information

[ HS Code ]:
2915709000

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%