N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

Names

[ Name ]:
N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

[Synonym ]:
COLLAGENASE SUBSTRATE II
EINECS 232-582-9
COLLAGENASE GRADE II
FA-LEU-GLY-PRO-ALA-OH
clostridiopeptidase
COLLAGENASE GRADE I

Biological Activity

[Description]:

FA-Leu-Gly-Pro-Ala-OH is a substrate of microbial collagenase[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Hydrolysis of the Leu-Gly bond of phenylazobenzyl-oxycarbonyl-L-Pro-L-Leu-Gly-L-Pro-D-Arg (a substrate of microbial collagenases) by treponemes isolated from the subgingival plaque of periodontitis patients. Current Microbiology 20, 69-74 (1990).

Chemical & Physical Properties

[ Density]:
1.269g/cm3

[ Boiling Point ]:
859.8ºC at 760 mmHg

[ Molecular Formula ]:
C₂₃H₃₂N₄O₇

[ Molecular Weight ]:
476.52300

[ Flash Point ]:
473.8ºC

[ Exact Mass ]:
476.22700

[ PSA ]:
158.05000

[ LogP ]:
1.63080

[ Index of Refraction ]:
1.564

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

Aeromonas piscicola AH-3 expresses an extracellular collagenase with cytotoxic properties.

Lett. Appl. Microbiol. 60(3) , 288-97, (2015)

The aim of this study was to investigate the presence and the phenotypic expression of a gene coding for a putative collagenase. This gene (AHA_0517) was identified in Aeromonas hydrophila ATCC 7966 g...

Cell-associated collagenolytic activity by Candida albicans.

Mycopathologia 153(3) , 125-8, (2002)

Cell associated collagenolytic activity of Candida albicans was quantified by measuring the degradation of synthetic peptide 2-furanacryloyl-Leu-Gly-Pro-Ala (FALGPA), which is a specific substrate for...

University of Wisconsin solution inhibits the class II collagenase within crude Clostridium histolyticum collagenase.

Transplant. Proc. 27(6) , 3286, (1995)

Related Compounds

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