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p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside

Names

[ CAS No. ]:
77640-21-2

[ Name ]:
p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside

[Synonym ]:
p-Nitrophenyl 2-O-(|A-L-fucopyranosyl)-|A-D-galactopyranoside
W0352
4-Nitrophenyl 2-O-(6-Deoxy-|A-L-galactopyranosyl)-|A-D-galactopyranoside
Fuc1-|A-2Gal-|A-PNP

Biological Activity

[Description]:

4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. R A DiCioccio, et al. Synthesis and use of p-nitrophenyl-2-O-(alpha-L-fucopyranosyl)-beta-D-galactopyranoside for the rapid detection of substrate-specific alpha-L-fucosidases. Anal Biochem. 1981 Feb;111(1):176-83.

Chemical & Physical Properties

[ Melting Point ]:
233-236ºC dec.

[ Molecular Formula ]:
C18H25NO12

[ Molecular Weight ]:
447.39100

[ Exact Mass ]:
447.13800

[ PSA ]:
204.12000

Related Compounds

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