phenyl-(3-phenyloxiran-2-yl)methanone

Names

[ Name ]:
phenyl-(3-phenyloxiran-2-yl)methanone

[Synonym ]:
TRANS-2-BENZOYL-3-PHENYLOXIRANE
trans-2-Benzoyl-3-phenyloxirane,trans-Benzalacetophenone oxide
2,4,4-TRIMETHYL-1-PENTENE (NO BULK SALES ALLOWED)
TRANS-BENZALACETOPHENONE OXIDE
trans-chalconeoxide
trans-2,3-epoxy-1,3-diphenyl-1-propanone
TRANS-1,3-DIPHENYL-2,3-EPOXYPROPAN-1-ONE
trans-phenyl(3-phenyloxiranyl)methanone
3-epoxy-3-phenyl-trans-propiophenon

Chemical & Physical Properties

[ Density]:
1.209g/cm3

[ Boiling Point ]:
374.1ºC at 760 mmHg

[ Melting Point ]:
86-89ºC(lit.)

[ Molecular Formula ]:
C₁₅H₁₂O₂

[ Molecular Weight ]:
224.25500

[ Flash Point ]:
174ºC

[ Exact Mass ]:
224.08400

[ PSA ]:
29.60000

[ LogP ]:
3.00940

[ Index of Refraction ]:
1.617

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UH1589300

CHEMICAL NAME :: Propiophenone, 2,3-epoxy-3-phenyl-, trans-

CAS REGISTRY NUMBER :: 7570-86-7

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H12-O2

MOLECULAR WEIGHT :: 224.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 1 mg/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 169,71,1986

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UH1589300

Articles

Highly enantioselective epoxidation of 2,4-diarylenones by using dimeric cinchona phase-transfer catalysts: enhancement of enantioselectivity by surfactants.

Angew. Chem. Int. Ed. Engl. 44(9) , 1383-5, (2005)

Anti-inflammatory effects of trans-1,3-diphenyl-2,3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.

Food Chem. Toxicol. 53 , 371-5, (2013)

To assess the potential therapeutic properties of trans-1,3-diphenyl-2,3-epoxypropane-1-one (DPEP), its anti-inflammatory effects were investigated in lipopolysaccharide (LPS)-stimulated mouse macroph...

Structure-mutagenicity relationships of chalcones and their oxides in the Salmonella assay.

Mutat. Res. 169(3) , 71-9, (1986)

31 p-monosubstituted chalcones (E-1, 3-diphenylpropene-1-one) and the corresponding oxides (E-1-benzoyl-2-phenyloxirane) were tested for mutagenic activity on two strains of Salmonella typhimurium (TA...