Bis-PEG5-NHS ester

Names

[ Name ]:
Bis-PEG5-NHS ester

[Synonym ]:
Bis-PEG5-NHS ester
AmbotzPEG1435
BIS-SUCCINIMIDYL-4,7,10,13,16-PENTAOXANONADECANE-1,19-DIOATE
B3728
Bis-dPEG5-NHS ester

Biological Activity

[Description]:

Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₂N₂O₁₃

[ Molecular Weight ]:
532.49500

[ Exact Mass ]:
532.19000

[ PSA ]:
173.51000

MSDS

Click to get detail MSDS

Related Compounds

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