H-Leu-OMe.HCl

Names

[ Name ]:
H-Leu-OMe.HCl

[Synonym ]:
Methyl L-leucinate hydrochloride (1:1)
L-Leucine, methyl ester, hydrochloride (1:1)
EINECS 231-375-0
L-Leucine, methyl ester, hydrochloride
MFCD00012494
methyl (2S)-2-amino-4-methylpentanoate,hydrochloride
H-Leu-OMe·HCl
H-Leu-OMe.HCl

Biological Activity

[Description]:

H-Leu-OMe.HCl is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
0.955 g/cm3

[ Boiling Point ]:
169.2ºC at 760 mmHg

[ Melting Point ]:
151-153 °C(lit.)

[ Molecular Formula ]:
C₇H₁₆ClNO₂

[ Molecular Weight ]:
181.660

[ Exact Mass ]:
181.086960

[ PSA ]:
52.32000

[ LogP ]:
2.03510

[ Index of Refraction ]:
13 ° (C=2, H2O)

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29224995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Primary in vitro immunization with multimeric synthetic peptides of HIV-1 envelope glycoproteins: generation of neutralizing human monoclonal antibodies.

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Peripheral blood lymphocytes from healthy HIV-1 seronegative donors were immunized in vitro with the following synthetic peptides: (i) an octameric poly-L-lysine conjugated peptide of the HIV-1MN V3 l...