Aluminium chloride
Names
[ CAS No. ]:
7446-70-0
[ Name ]:
Aluminium chloride
[Synonym ]:
EINECS 231-208-1
Aluminium chloride
Aluminum chloride anhydrous
MFCD00003422
Aluminum chloride
Chemical & Physical Properties
[ Density]:
2.44
[ Boiling Point ]:
180°C
[ Melting Point ]:
194 °C
[ Molecular Formula ]:
AlCl3
[ Molecular Weight ]:
133.340
[ Flash Point ]:
88 °C
[ Exact Mass ]:
131.888092
[ LogP ]:
2.06850
[ Appearance of Characters ]:
powder
[ Vapour Pressure ]:
1 mm Hg ( 100 °C)
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable, but reacts violently with water. Prolonged storage may lead to pressure build-up - vent container periodically. Incompatible with alcohols and a variety of other materials (see complete MSDS sheet for full list).
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BD0525000
- CHEMICAL NAME :
- Aluminum chloride
- CAS REGISTRY NUMBER :
- 7446-70-0
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 38
- MOLECULAR FORMULA :
- Al-Cl3
- MOLECULAR WEIGHT :
- 133.33
- WISWESSER LINE NOTATION :
- AL G3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3450 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Gastrointestinal - other changes Kidney, Ureter, Bladder - hematuria
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 315 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 390 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9380 mg/kg/52D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - changes in phosphorus
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2307 mg/kg/26W-I
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 gm/kg/48W-C
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - alteration of operant conditioning
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 99 mg/kg/5D-I
- TOXIC EFFECTS :
- Musculoskeletal - osteomalacia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/kg/3D-I
- TOXIC EFFECTS :
- Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 8421 mg/kg/40D-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - changes in metals, not otherwise specified
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 11512 mg/kg
- SEX/DURATION :
- female 8-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5723 mg/kg
- SEX/DURATION :
- female 1-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - other neonatal measures or effects Reproductive - Effects on Newborn - behavioral
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 900 mg/kg
- SEX/DURATION :
- female 15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - delayed effects
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 375 mg/kg
- SEX/DURATION :
- female 9-13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 500 mg/kg
- SEX/DURATION :
- female 14-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 425 mg/kg
- SEX/DURATION :
- multigenerations
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 444 mg/kg
- REFERENCE :
- NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 15,180,1972 *** REVIEWS *** ACGIH TLV-TWA 2 mg(Al)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 2 mg(Al)/m3 JAN 1993 OEL-BELGIUM:TWA 2 mg(Al)/m3 JAN 1993 OEL-DENMARK:TWA 2 mg(Al)/m3 JAN 1993 OEL-FRANCE:TWA 2 mg(Al)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 2 mg(Al)/m3 JAN 1993 OEL-RUSSIA:TWA 2 mg(Al)/m3 JAN 1993 OEL-SWEDEN:TWA 2 mg(Al)/m3 JAN 1993 OEL-SWITZERLAND:TWA 2 mg(Al)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 2 mg(Al)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 04605 No. of Facilities: 3476 (estimated) No. of Industries: 29 No. of Occupations: 34 No. of Employees: 17152 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 04605 No. of Facilities: 2230 (estimated) No. of Industries: 32 No. of Occupations: 68 No. of Employees: 49913 (estimated) No. of Female Employees: 17460 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314-H372-H373
[ Supplemental HS ]:
Reacts violently with water.
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Target Organs ]:
Central nervous system, Lungs
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S28;S45
[ RIDADR ]:
UN 1726 8/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
BD0525000
[ Packaging Group ]:
II
[ Hazard Class ]:
8.0
[ HS Code ]:
2827320000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2827320000
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