2-[(2-Bromobenzyl)oxy]benzoic acid

Names

[ Name ]:
2-[(2-Bromobenzyl)oxy]benzoic acid

[Synonym ]:
2-(2-bromobenzo[d]thiazol-6-yl)acetonitrile
2-(2-bromoacetamido)-3-cyano-4,5-dimethylacetophenone
Acetamide,N-(6-acetyl-2-cyano-3,4-dimethylphenyl)-2-bromo
2-[(2-Bromobenzyl)oxy]benzoic acid
2-(2-bromobenzyloxy)benzoic acid
Benzoic acid, 2-[(2-bromophenyl)methoxy]-

Biological Activity

[Description]:

ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[In Vitro]

ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild type, Ras protein wild type, GTP-binding protein (Rab7), Rac1 protein activated mutant, Rac1 protein wild type, and Ras protein activated mutant with EC50 values of 50.11 nM, 102.32 nM, 109.64 nM, 20.41 nM, 81.28 nM, 151.35 nM, and 93.32 nM, respectively[1].

[References]

[1]. Zurab Surviladze, et al. Three small molecule pan activator families of Ras-related GTPases.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
445.4±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₁BrO₃

[ Molecular Weight ]:
307.139

[ Flash Point ]:
223.2±23.2 °C

[ Exact Mass ]:
305.989136

[ PSA ]:
46.53000

[ LogP ]:
3.92

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.629

Safety Information

[ HS Code ]:
2918990090

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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