m-Chloramphenicol

Names

[ Name ]:
m-Chloramphenicol

[Synonym ]:
ERYTHRO-M-CHLORAMPHENICOL
m-nitro-threo-Chloramphenicol
M-CHLORAMPHENICOL

Biological Activity

[Description]:

m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Berendsen BJ, et al. Discrimination of eight chloramphenicol isomers by liquid chromatography tandem mass spectrometry in order to investigate the natural occurrence of chloramphenicol. Anal Chim Acta. 2011;700(1-2):78-85.

[2]. Polikanov YS, et al. The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics. Front Mol Biosci. 2018;5:48. Published 2018 May 14.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₂Cl₂N₂O₅

[ Molecular Weight ]:
323.12900

[ Exact Mass ]:
322.01200

[ PSA ]:
115.38000

[ LogP ]:
1.82310

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H350

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
45

[ Safety Phrases ]:
53-45

[ RIDADR ]:
NONH for all modes of transport

Articles

Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.

Infect. Immun. 76(4) , 1333-9, (2008)

Thymidine-dependent small-colony variants (SCVs) of Staphylococcus aureus are frequently associated with persistent and recurrent infections in cystic fibrosis patients. The phenotypic appearance of S...

The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells.

PLoS Biol. 8 , (2010)

The protozoan parasite Theileria inhabits the host cell cytoplasm and possesses the unique capacity to transform the cells it infects, inducing continuous proliferation and protection against apoptosi...

Airtight storage of moist wheat grain improves bioethanol yields.

Biotechnol. Biofuels 2(1) , 16, (2009)

Drying is currently the most frequently used conservation method for cereal grain, which in temperate climates consumes a major part of process energy. Airtight storage of moist feed grain using the b...

Related Compounds

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