S(+)-4-Aminohexenoic acid
Names
[ CAS No. ]:
74046-07-4
[ Name ]:
S(+)-4-Aminohexenoic acid
[Synonym ]:
(S)-4-aminohex-5-enoic acid
(4S)-4-Aminohex-5-enoic acid
(4S)-4-Amino-5-hexenoic acid
S(+)-|A-Vigabatrin
5-Hexenoic acid,4-amino-,(+)
4-amino-5-hexenoic acid
(S)-vigabatrin(R)
S(+)-4-Aminohexenoic acid
(S)-Vigabatrin
(S)-4-Amino-5-hexenoic Acid
5-Hexenoic acid, 4-amino-, (4S)-
(+)-Vigabatrin
S(+)-γ-Vigabatrin
MFCD00274076
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
277.7±28.0 °C at 760 mmHg
[ Melting Point ]:
166 - 167 °C
[ Molecular Formula ]:
C6H11NO2
[ Molecular Weight ]:
129.157
[ Flash Point ]:
121.7±24.0 °C
[ Exact Mass ]:
129.078979
[ PSA ]:
63.32000
[ LogP ]:
-0.10
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.483
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
Soluble to 100 mM in water
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Neuropharmacology 25 , 617-625, (1986)
A preferential effect of valproate on gamma-aminobutyric acid (GABA) in the nerve terminal compartment has been proposed. Gamma-vinyl GABA, an irreversible inhibitor of GABA-transaminase (GABA-T) caus...
An analysis of the cortical and striatal involvement in dyskinesia induced in rats by intracerebral injection of GABA-transaminase inhibitors and picrotoxin.Eur. J. Pharmacol. 62 , 319, (1980)
Unilateral intrastriatal injection of various substances induces a characteristic dyskinetic syndrome in rats. These substances include picrotoxin as well as a series of irreversible GABA-transaminase...