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Naringenin chalcone

Names

[ CAS No. ]:
73692-50-9

[ Name ]:
Naringenin chalcone

[Synonym ]:
2',4',6',4-tetrahydroxydihydrochalcone
2,4,6-Trihydroxyphenyl-4'-hydroxybenzyl Ketone
4-hydroxybenzyl-2,4,6-trihydroxyphenyl ketone
1-(2,4,6-trihydroxyphenyl)-2-(4-hydroxyphenyl)ethanone
2',4',4,6'-tetrahydroxychalcone
2′,4′,6′,4-tetrahydroxychalcone
(2E)-3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-propen-1-one
naringenin chalcone
2,4,6,4'-tetrahydroxydeoxybenzoin
2-(4-hydroxyphenyl)-1-(2,4,6-trihydroxy-phenyl)-ethanone
4,2',4',6'-Tetrahydroxy-chalkon
2-(p-Hydroxyphenyl)phloroacetophenone
2-Propen-1-one, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-
2-Propen-1-one, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, (2E)-
2,4,4',6-tetrahydroxy deoxybenzoin
|A-(4'-Hydroxyphenyl)phloroacetophenone
2',4,4',6'-Tetrahydro-chalcon

Biological Activity

[Description]:

Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone has anti-inflammatory and antiallergic activities[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Escribano-Ferrer E, et al. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.J Nat Prod. 2019 Feb 22;82(2):177-182.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
538.7±50.0 °C at 760 mmHg

[ Melting Point ]:
173-174 ºC

[ Molecular Formula ]:
C15H12O5

[ Molecular Weight ]:
272.253

[ Flash Point ]:
293.6±26.6 °C

[ Exact Mass ]:
272.068481

[ PSA ]:
97.99000

[ LogP ]:
3.13

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.748

[ Storage condition ]:
-20℃

Related Compounds