p-Coumaric acid ethyl ester

Names

[ Name ]:
p-Coumaric acid ethyl ester

[Synonym ]:
Ethyl (2E)-3-(4-hydroxyphenyl)acrylate
Ethyl (2E)-3-(4-hydroxyphenyl)-2-propenoate
2-Propenoic acid, 3-(4-hydroxyphenyl)-, ethyl ester, (2E)-

Biological Activity

[Description]:

p-Coumaric Acid Ethyl Ester is the ethyl ester of p-Coumaric acid[1]. p-Coumaric Acid is a potential immunosuppressive agent in treating autoimmune inflammatory diseases like rheumatoid arthritis[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. T. Silva, et al. Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors. RSC Advances. Issue 72, 2015.

[2]. Pragasam SJ, et al. Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats. Inflammation. 2013 Feb;36(1):169-76.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
320.2±17.0 °C at 760 mmHg

[ Melting Point ]:
65-68 °C

[ Molecular Formula ]:
C₁₁H₁₂O₃

[ Molecular Weight ]:
192.211

[ Flash Point ]:
136.5±13.7 °C

[ Exact Mass ]:
192.078644

[ PSA ]:
46.53000

[ LogP ]:
2.17

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.581

Related Compounds

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