Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)-
Names
[ CAS No. ]:
73341-73-8
[ Name ]:
Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)-
[Synonym ]:
macbecin II
Chemical & Physical Properties
[ Density]:
1.19g/cm3
[ Boiling Point ]:
698.9ºC at 760 mmHg
[ Molecular Formula ]:
C30H44N2O8
[ Molecular Weight ]:
560.67900
[ Flash Point ]:
376.5ºC
[ Exact Mass ]:
560.31000
[ PSA ]:
149.57000
[ LogP ]:
5.81680
[ Index of Refraction ]:
1.565
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OL9056000
- CHEMICAL NAME :
- Macbecin II
- CAS REGISTRY NUMBER :
- 73341-73-8
- LAST UPDATED :
- 198509
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C30-H44-N2-O8.H2-O
- MOLECULAR WEIGHT :
- 578.78
- WISWESSER LINE NOTATION :
- T6-19- A GMV IU KU OU&TJ AQ DQ I1 M1 NOVZ O1 Q1 RO1 SO1 U1 VO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 24,321,1983
Precursor & DownStream
Precursor
DownStream
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.