Pyridine-d5

Names

[ Name ]:
Pyridine-d5

[Synonym ]:
EINECS 230-720-2
4-Methyl-benzenamine-d7
[D5]pyridine
Perdeutero-p-toluidin
4-Aminotoluene-d7
Pyridine-d
(H)Pyridine
4-Toluidine-d7 (Major)
4-Methyl-1-aminobenzene-d7
4-Methylphenylamine-d7
2,3,5,6-tetradeuterio-4-trideuteriomethyl-aniline
perdeuteropyridine
4-Methylaniline-d7
Pyridine-d5
1-Amino-4-methylbenzene-d7
MFCD00044639
2,4,5,6-tetradeuterio-pyridine

Biological Activity

[Description]:

Pyridine-d5 is the deuterium labeled Pyridine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
115.3±0.0 °C at 760 mmHg

[ Melting Point ]:
-41ºC

[ Molecular Formula ]:
C₅D₅N

[ Molecular Weight ]:
84.131

[ Flash Point ]:
20.0±0.0 °C

[ Exact Mass ]:
84.073586

[ PSA ]:
12.89000

[ LogP ]:
0.73

[ Vapour Pressure ]:
22.8±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.501

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Highlyflammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R20/21/22

[ Safety Phrases ]:
S26-S28

[ RIDADR ]:
UN1282

[ WGK Germany ]:
3

[ Packaging Group ]:
II

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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