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γ1-MSH

Names

[ CAS No. ]:
72629-65-3

[ Name ]:
γ1-MSH

[Synonym ]:
GAMMA1-MELANOCYTE STIMULATING HORMONE
GAMMA1-MSH
g1-MSH
YVMGHFRWDRFG-NH2
H-TYR-VAL-MET-GLY-HIS-PHE-ARG-TRP-ASP-ARG-PHE-NH2
δ1-MSH, amide

Biological Activity

[Description]:

γ1-MSH is a melanocortin MC3 receptor agonist, with a Ki of 34 nM for the rat MC3 receptor. γ1-MSH displays ~40-fold selectivity over MC4 (Ki=1318 nM)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

[References]

[1]. Lindblom J, et al. Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain. Brain Res. 1998;810(1-2):161-171. doi:10.1016/s0006-8993(98)00918-4

Chemical & Physical Properties

[ Molecular Formula ]:
C72H97N21O14S

[ Molecular Weight ]:
1512.74000

[ Exact Mass ]:
1511.72000

[ PSA ]:
611.21000

[ LogP ]:
5.50370

Related Compounds