Suc-Ala-Ala-Pro-Phe-pNA

Names

[ Name ]:
Suc-Ala-Ala-Pro-Phe-pNA

[Synonym ]:
SUC-ALA-ALA-PRO-PHE-PARANITROANILIDE
N-SUCCINYL-ALA-ALA-PRO-PHE P-NITROANILIDE
Cathepsin G Substrate I
CATHEPSIN G SUBSTRATE I,COLORIMETRIC
SAAPNA
SUC-AAPF-PNA
N-SUCCINYL-ALA-ALA-PRO-PHE-PNA
SUCCINYL-ALA-ALA-PRO-PHE-P-NITROANILIDE
N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine p-nitroanilide
N-Succ-Ala-Ala-Pro-Phe-p-nitroanilide
L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-
N-Succinyl-Ala-Ala-Pro-Phe 4-nitroanilide
N-(3-Carboxypropanoyl)alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide
MFCD00077161

Biological Activity

[Description]:

Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Suc-AAPF-pNA can be used for the Measurement of free and membrane-bound cathepsin G in human neutrophils[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Sylvie Attucci, et al. Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates. Biochem J. 2002 Sep 15;366(Pt 3):965-70.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1072.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₃₆N₆O₉

[ Molecular Weight ]:
624.642

[ Flash Point ]:
602.6±34.3 °C

[ Exact Mass ]:
624.254395

[ PSA ]:
219.83000

[ LogP ]:
2.58

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMF: 25 mg/mL, clear, light yellow

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

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