Flurofamide

Names

[ Name ]:
Flurofamide

[Synonym ]:
Flurofamide
EU-4534
Flurofamine
Flurfamide

Biological Activity

[Description]:

Flurofamide is a potent bacterial urease inhibitor with potential clinical utility in the treatment of infection induced urinary stones[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Millner OE Jr, et al. Flurofamide: a potent inhibitor of bacterial urease with potential clinical utility in the treatment of infection induced urinary stones. J Urol. 1982 Feb;127(2):346-50.

Chemical & Physical Properties

[ Density]:
1.457g/cm3

[ Molecular Formula ]:
C₇H₉FN₃O₂P

[ Molecular Weight ]:
217.13700

[ Exact Mass ]:
217.04200

[ PSA ]:
108.02000

[ LogP ]:
2.37250

[ Index of Refraction ]:
1.574

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV3458100

CHEMICAL NAME :: Benzamide, N-(diaminophosphinyl)-4-fluoro-

CAS REGISTRY NUMBER :: 70788-28-2

LAST UPDATED :: 199112

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H9-F-N3-O2-P

MOLECULAR WEIGHT :: 217.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,734,1982

Related Compounds

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