Phloridzin

Names

[ Name ]:
Phloridzin

[Synonym ]:
2'-O-GLUCOSYL-4',6',4-TRIHYDROXYDIHYDROCHALCONE
phloridzin from apple wood
Phloretin 2'-b-D-glucopyranoside
3,5-Dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl β-D-glucopyranoside dihydrate
MFCD00006591
1-Propanone, 1-[2-(β-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-, hydrate (1:2)
PHLORIDZIN
EINECS 200-487-1
PHLORIDZIN(RG)

Biological Activity

[Description]:

Phlorizin (dihydrate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Boiling Point ]:
770ºC at 760 mmHg

[ Melting Point ]:
113-114 °C(lit.)

[ Molecular Formula ]:
C₂₁H₂₈O₁₂

[ Molecular Weight ]:
472.440

[ Flash Point ]:
270.7ºC

[ Exact Mass ]:
472.158081

[ PSA ]:
195.60000

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UC2080000

Articles

Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice.

FASEB J. 29 , 3537-48, (2015)

Adipose tissue macrophages (ATMs) play an important role in the pathogenesis of obese type 2 diabetes. High-fat diet (HFD)-induced obesity has been shown to lead to ATM accumulation in rodents; howeve...

Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin.

Proc. Natl. Acad. Sci. U. S. A. 106 , 10638-43, (2009)

Adjustable control of therapeutic transgenes in engineered cell implants after transdermal and topical delivery of nontoxic trigger molecules would increase convenience, patient compliance, and elimin...