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Coelenterazine 400 a

Names

[ CAS No. ]:
70217-82-2

[ Name ]:
Coelenterazine 400 a

[Synonym ]:
BlueSyn C
DI-DEHYDRO COELENTERAZINE
Imidazo[1,2-a]pyrazin-3(7H)-one, 6-phenyl-2,8-bis(phenylmethyl)-
2,8-Dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one
Coelenterazine 400 a
BISDEOXYCOELENTERAZINE
C-7010
coelenterazine-hh

Biological Activity

[Description]:

Coelenteramine 400a (Bisdeoxycoelenterazine), a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a, RLuc can emit blue light at 395 nm[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Levi J, et, al. Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays. J Am Chem Soc. 2007 Oct 3;129(39):11900-1.

[2]. Bertrand L, et, al. The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS). J Recept Signal Transduct Res. Feb-Nov 2002;22(1-4):533-41.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
551.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H21N3O

[ Molecular Weight ]:
391.464

[ Flash Point ]:
287.3±32.9 °C

[ Exact Mass ]:
391.168457

[ PSA ]:
50.16000

[ LogP ]:
4.84

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.662

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds