2'-O-t-Butyldimethylsilyl adenosine

Names

[ Name ]:
2'-O-t-Butyldimethylsilyl adenosine

[Synonym ]:
Adenosine,2'-O-[(1,1-dimethylethyl)dimethylsilyl]

Biological Activity

[Description]:

2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₇N₅O₄Si

[ Molecular Weight ]:
381.50200

[ Exact Mass ]:
381.18300

[ PSA ]:
128.54000

[ LogP ]:
1.63070

2'-O-t-Butyldimethylsilyl adenosine

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds