2-Amino-9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine

Names

[ Name ]:
2-Amino-9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine

[Synonym ]:
MFCD25542506
9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purin-2-amine
9H-Purin-2-amine, 9-(2-C-methyl-β-D-ribofuranosyl)-

Biological Activity

[Description]:

2-Ami no-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
674.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅N₅O₄

[ Molecular Weight ]:
281.27

[ Flash Point ]:
361.8±34.3 °C

[ Exact Mass ]:
281.112396

[ LogP ]:
0.17

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.823