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Dansyl-Glu-Gly-Arg-chloromethylketone

Names

[ CAS No. ]:
69024-84-6

[ Name ]:
Dansyl-Glu-Gly-Arg-chloromethylketone

[Synonym ]:
EGRck
Degr-CK
Dansyl-ggack
Dggacmk
Dansyl-Glu-Gly-Arg-Chloromethylketone
glycinamide,n-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-l-|A-glutamyl-n-[(1s)-1-(2-chloroacetyl)-4-[(diaminomethylene)amino]butyl]

Biological Activity

[Description]:

Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone inhibits activated porcine factor IX[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease
Research Areas >> Others

[References]

[1]. Lollar P, et, al. Inhibition of activated porcine factor IX by dansyl-glutamyl-glycyl-arginyl-chloromethylketone. Arch Biochem Biophys. 1984 Sep;233(2):438-46.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H36ClN7O7S

[ Molecular Weight ]:
626.12

[ Exact Mass ]:
625.20900

[ PSA ]:
232.26000

[ LogP ]:
3.53410

Related Compounds