<Suppliers Price>

CBR 5884

Names

[ CAS No. ]:
681159-27-3

[ Name ]:
CBR 5884

[Synonym ]:
Ethyl 5-(2-furoylamino)-3-methyl-4-thiocyanato-2-thiophenecarboxylate
2-Thiophenecarboxylic acid, 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-, ethyl ester

Biological Activity

[Description]:

CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[References]

[1]. Edouard Mullarky et al. Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancersProc Natl Acad Sci U S A, 2016 Feb 16, 113(7):1778-83.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
378.1±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H12N2O4S2

[ Molecular Weight ]:
336.386

[ Flash Point ]:
182.5±27.9 °C

[ Exact Mass ]:
336.023834

[ LogP ]:
4.15

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
2-8℃

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.