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Deprodone

Names

[ CAS No. ]:
6795-60-4

[ Name ]:
Deprodone

[Synonym ]:
Nor-progestelea
17-Vinyl-19-nortestosterone
Norvinisterone
Norvinisterona [INN-Spanish]
SC 4641
Norvinisteronum [INN-Latin]
Neoprogestin

Chemical & Physical Properties

[ Density]:
1.11g/cm3

[ Boiling Point ]:
444ºC at 760 mmHg

[ Molecular Formula ]:
C20H28O2

[ Molecular Weight ]:
300.43500

[ Flash Point ]:
189.2ºC

[ Exact Mass ]:
300.20900

[ PSA ]:
37.30000

[ LogP ]:
4.04530

[ Index of Refraction ]:
1.565

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC8899550
CHEMICAL NAME :
19-Nor-17-alpha-pregna-4,20-dien-3-one, 17-hydroxy-
CAS REGISTRY NUMBER :
6795-60-4
LAST UPDATED :
199606
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H28-O2
MOLECULAR WEIGHT :
300.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
28 mg/kg
SEX/DURATION :
male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,500,1958
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
112 mg/kg
SEX/DURATION :
male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,500,1958
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
8 mg/kg
SEX/DURATION :
male 3 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,29,1965
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
500 ug/kg
SEX/DURATION :
female 5 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 142,469,1962

Related Compounds