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11-Dehydro-thromboxane B2

Names

[ CAS No. ]:
67910-12-7

[ Name ]:
11-Dehydro-thromboxane B2

[Synonym ]:
11-Dehydro Thromboxane B2
7-{(2R,3S,4S)-4-Hydroxy-2-[(3S)-3-hydroxy-1-octen-1-yl]-6-oxotetrahydro-2H-pyran-3-yl}-5-heptenoic acid

Biological Activity

[Description]:

11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite


[References]

[1]. Simeone P, et al. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis. Ageing Res Rev. 2018 Dec;48:51-78.  

[2]. Lopez LR, et al. Platelet thromboxane (11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease. World J Diabetes. 2014 Apr 15;5(2):115-27.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
588.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H32O6

[ Molecular Weight ]:
368.46

[ Flash Point ]:
202.9±23.6 °C

[ Exact Mass ]:
368.219879

[ PSA ]:
104.06000

[ LogP ]:
1.92

[ Vapour Pressure ]:
0.0±3.7 mmHg at 25°C

[ Index of Refraction ]:
1.552

Related Compounds